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Postdoctoral Researcher in Virology

Geplaatst 7 mrt. 2025
Delen:
Werkervaring
1 tot 10 jaar
Full-time / part-time
Full-time
Functie
Salaris
€ 3.378 - € 5.331 per maand
Soort opleiding
Taalvereisten
Engels (Vloeiend)
Nederlands (Vloeiend)
Deadline
31 mrt. 2025 00:00

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We are seeking a highly motivated postdoctoral researcher to join our dynamic research team as part of a recently funded public private partnership between Utrecht University & MSD Animal Health. This project is focused on developing broad-protective vaccines against Infectious Bronchitis Virus (IBV), a major avian coronavirus that threatens global poultry production, causing respiratory disease, reduced growth, poor egg quality, and increased antibiotic use. IBV-related losses amount to hundreds of millions of euros annually, impacting both food security and animal welfare.

Your job

Current vaccines, which are based on live-attenuated and inactivated virus formulations, require constant updates due to the virus’s evolution and emerging serotypes. This project, a public-private partnership between Utrecht University and MSD Animal Health, aims to develop broad-protective that induce a long-lasting immunity and advanced surveillance tools to combat IBV infections in the field more effectively.To address the limitations of existing vaccines, we focus on:

  • structure-based antigen design – identifying and engineering key viral antigens to elicit cross-protective immune responses;
  • viral vector technology – optimising delivery platforms to enhance vaccine efficacy, local immunity, and durability;
  • immune profiling – understanding the mechanisms behind protective immunity after vaccination or infection in chickens, crucial for designing next-generation vaccines;
  • surveillance innovation – developing advanced diagnostic tools to monitor IBV evolution and antigenic drift, to improve outbreak control strategies.

By integrating virology, immunology, and cutting-edge vaccine technology, we aim to improve poultry health, reduce disease outbreaks and minimize reliance on antibiotics.

As a postdoctoral researcher, you will play a central role in developing next-generation IBV vaccines. Your key responsibilities include:

  • leading experimental work on IBV vaccine development and immunity;
  • designing novel antigens for broad-spectrum protection;
  • exploring the optimal (viral) vector vaccine platforms for antigen delivery;
  • developing advanced serology tools to track chicken immunity against IBV;
  • collaborating with and co-supervising a PhD candidate;
  • collaborating with our industry partner and fellow researchers;
  • writing scientific articles and publishing your findings in scientific journals.

Your qualities

We are looking for a motivated researcher with:

  • a PhD in molecular virology, immunology, or a related field;
  • experience with techniques relevant to the role, which include molecular biology techniques (PCR, cloning), protein expression & characterization (ELISA, flow cytometry), virological techniques (virus propagation, pseudovirus system, hemagglutination assay), structural virology (single-particle cryoEM) and vaccine development & immune profiling. Please elaborate on your experience in your motivation letter;
  • a background in virology, particularly coronaviruses, is a plus;
  • preference for working at the intersection of fundamental and applied research;
  • excellent problem-solving skills and the ability to work independently as well as collaboratively;
  • a team player capable of managing multiple projects simultaneously;
  • strong written and verbal communication skills.

Our offer

  • A one-year contract with the possibility of extension up to three years following satisfactory performance;
  • a working week of 36 hours and a gross monthly salary between €3,378 and €5,331 in the case of full-time employment (salary scale 10 under Collective Labour Agreement for Dutch Universities (CAO NU));
  • 8% holiday pay and 8.3% year-end bonus;
  • a pension scheme, partially paid parental leave and flexible employment conditions based on the collective labor agreement for Dutch Universities.

We work on a better future. In order to do that, we join forces with academics, students, alumni, social partners, the government and the corporate world. Together, we look for sustainable solutions to the big challenges of today and tomorrow.

Educatie
Utrecht
7.000 medewerkers