Internship | Toxicity Testing of Microplastics

Internship opportunity: Toxicity Testing of Microplastics

About this position

Microplastics are increasingly recognized as environmental contaminants with potential health risks. Despite growing concern, the mechanisms by which microplastic particles affect human health remain unclear. One possible pathway is the induction of oxidative stress through increased production of reactive oxygen species (ROS).

In this internship, you will investigate whether exposure to microplastic particles leads to oxidative stress in cell models by measuring ROS generation.

In this internship, you will gain hands-on experience with cell culturing, microplastic particle handling, and in vitro toxicity testing. Next to common cytotoxicity assays, flow cytometry (FACS) will be used as a key method to quantify ROS levels and assess cellular responses. You’ll process and analyze experimental data, discuss findings in lab meetings, and present the results in reports.

You will be part of the RAPID (Risk Analysis of Product in Development) team located in Utrecht and the Human Cell Biology (HCB) research group located in Leiden. Importantly, the experimental work will be performed in TNO's research facilities in Leiden.

What we expect from you

We are looking for a motivated master's student in a relevant field (such as toxicology, biomedical sciences, or molecular biology) with hands-on experience in in vitro cultures (required) and preferably FACS. A background or strong interest in toxicology or particle research is appreciated. The ideal candidate can work independently, is persistent, eager to learn and to overcome challenges, communicates well, and enjoys teamwork.

What you'll get in return

• A highly professional, innovative internship environment, within a team of top experts.
• A suitable internship allowance (615 euro for wo-, hbo- and mbo-students, for a full-time internship).
• Possibility of eight hours of free leave per internship month (for a full-time internship).
• A free membership of Jong TNO, where you can meet other TNO professionals and join several activities, such as sports activities, (work-related) courses or the yearly ski-trip.
• Use of a laptop.
• An allowance for travel expenses in case you don’t receive an OV-card.

TNO as an employer

At TNO, we innovate for a healthier, safer and more sustainable life. And for a strong economy. Since 1932, we have been making knowledge and technology available for the common good. We find each other in wonder and ingenuity. We are driven to push boundaries. There is all the space and support for your talent and ambition. You work with people who will challenge you: who inspire you and want to learn from you. Our state-of-the-art facilities are there to realize your vision. What you do at TNO matters: impact makes the difference. Because with every innovation you contribute to tomorrow’s world.

More information about this vacancy?

Lora Gerber

E-mailadres: lora.gerber@tno.nl