Lab Manager (Part-time or full time)

The Tanenbaum lab studies how cells and viruses control gene expression at the level of mRNA regulation. We develop and apply advanced microscopy approaches that allow us to visualize the translation and regulation of individual mRNA molecules in living cells. Our work combines quantitative live-cell imaging, molecular biology, and genetic engineering to uncover the molecular mechanisms that control gene expression in human cells and during RNA virus infection. Using these approaches, we aim to understand how gene expression dynamics shape cellular behavior and disease processes.

We are looking for a motivated and organized lab manager to support our research program.

Lab Manager (Part-time or full time)

Description of the project

The position combines experimental work with laboratory organization and management. The successful candidate will work closely with members of the Tanenbaum lab and collaborate with other research groups and facilities at the Hubrecht Institute.

Responsibilities

The lab manager will support the daily operation of the laboratory and contribute to research projects. Tasks will include:

• Performing molecular biology and cell culture experiments
• Supporting live-cell microscopy experiments, sample preparation and analysis
• Assisting with cloning, cell line generation, and assay development
• General laboratory organization (ordering, inventory, equipment coordination)
• Helping maintain laboratory protocols and documentation
• Supporting lab members with experimental setup and troubleshooting

Requirements

We are looking for a motivated and reliable technician with an HLO background and interest in molecular and cell biology.

Preferred qualifications:

• BSc/MSc degree (or equivalent) in Biology, Life Sciences, or related field
• Experience with molecular biology techniques (e.g. cloning, PCR, DNA/RNA work)
• Experience with mammalian cell culture
• Fluorescence analysis methods, including microscopy and FACS
• Genome modification using CRISPR
• Strong organizational skills and interest in lab management
• Ability to work independently as well as in a team
• Proactive attitude and good independent problem-solving skills
• Excellent communication skills in English (working language of the institute)

About the Hubrecht Institute

The Hubrecht Institute is a research institute focused on molecular and developmental biology. Because of the dynamic character of the research, the institute has a variable number of research groups, around 20, that do fundamental, multidisciplinary research on healthy and diseased cells, tissues and organisms. The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), situated on Utrecht Science Park. Since 2008, the institute is affiliated with the UMC Utrecht, advancing the translation of research to the clinic. The Hubrecht Institute has a partnership with the European Molecular Biology Laboratory (EMBL).

Terms of employment

The KNAW offers its staff an excellent package of secondary benefits. A package that meets the different needs of employees depending on their stage of life, lifestyle or career ambitions. For example, by working an extra two hours a week, it is possible to increase the number of days off from 29 to 41 days a year (with full-time employment).

Applying for a Certificate of Good Conduct can be part of the employment procedure.