Assistant professor or postdoc intestinal function and failure

Working at Amsterdam UMC

Assistant professor or postdoc intestinal function and failure

Would you like to take on the challenge of addressing pediatric intestinal failure in a multidisciplinary team?

The project

Intestinal failure is defined as “the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or fluids and electrolytes, such that intravenous supplementation is required to maintain health and/or growth”. Despite its profound impact, the underlying causes of chronic intestinal failure in children remain poorly understood, and effective therapeutic options are limited.

About your role

As an assistant professor, you will perform cutting-edge translational research focusing on chronic intestinal failure in children with our Tytgat Institute-based research team, while fostering collaboration with clinical colleagues at the Emma Center for Personalized Medicine (Emma CPM) and the pediatric gastroenterology team at Kinderbuikcentrum Amsterdam UMC. This interdisciplinary approach will allow you to bridge the gap between scientific research and clinical care.

In addition to your research responsibilities, you will contribute to teaching by mentoring students and PhD candidates, and translating newly acquired scientific insights into educational resources and knowledge-sharing initiatives. You will also participate in the (bio)medical curriculum, with teaching expected to constitute 10-20% of your time.

We expect you to actively contribute to securing research funding and expanding your research team, furthering the impact of your work and the department’s goals.

About you

You have:

• a PhD in Cell Biology, Medical Biology, or a related field;
• a strong track record in stem cell biology (pluripotent or tissue specific stem cells);
• a translational focus involving either regenerative cell or gene therapies, disease modelling and/or stem cell-based drug development.

You have a strong interest in intestinal development and/or function, with a particular focus on groundbreaking (stem) cell biology and genetics. You aim to uncover innovative therapies for children with chronic intestinal failure in a multidisciplinary team.

You demonstrate a track record of successful international collaboration and have the ability to secure competitive funding to expand your research program.

Fluency in both Dutch and English is essential, or a willingness to learn Dutch in the near future to integrate into our team and community.

Our offer

• The position is initially a temporary appointment for 24 months, with the possibility of extension based on performance.
• The salary depends on your education and experience. Employment conditions are in accordance with the Collective Agreement for University Medical Centers (CAO-UMC).
• Classification in salary scale 10 (postdoc): € 3.493 to € 5.504, or salary scale 11 (assistant professor): € 4.678 to € 6.402 gross per month. The salary is exclusive of any irregular hours allowances, holiday pay, and end-of-year bonus. In addition to a good basic salary, we offer 8.3% end-of-year bonus. From July 1st, 2025, there will be a salary increase of 3%.
• Vacation hours: 190,4 per year for fulltime and possibility to save additional hours.
• Free and unlimited access to our online learning environment GoodHabitz.
• Pension accrual with the ABP, of which we pay 70% of the premium.
• A reimbursement of your public transport expenses. Do you prefer to come by bike? Then we have a good bicycle scheme.
• An active staff association and Jong Amsterdam UMC association, both of which organize fun (sports) activities and events.

About your workplace

The primary appointment will be at the AMC location; secondment to the VUmc location is possible.

The Pediatric Abdominal Center at Emma Children’s Hospital/Amsterdam UMC is the leading expert center in the Netherlands for managing this condition, while the Tytgat Institute is a pioneer to pre-clinical research in liver and intestinal diseases. Together, our goal is to advance knowledge of the causes of intestinal failure and develop innovative therapies to improve outcomes for affected children.

Amsterdam UMC has an open culture. This means that we hope that everyone feels welcome in our organization and that we strive to offer equal opportunities to everyone. We therefore cordially invite all interested parties to respond to this vacancy.

During the publication period, applications will be handled continuously. If the vacancy is filled, it will be closed prematurely.

Contact:

• If you have any questions about this position, please feel free to contact Stan van de Graaf (Head Tytgat Institute, k.f.vandegraaf@amsterdamumc.nl), or Merit Tabbers (Head Pediatric Gastroenterology, m.m.tabbers@amsterdamumc.nl).
• More information about Emma CPM can be obtained from Prof. C. van Karnebeek, pediatrician for metabolic diseases, and/or Prof. M. van Haelst, clinical geneticist (co-directors of Emma Center for Personalized Medicine) via Joyce de Bree (emmacpm@amsterdamumc.nl).

A reference check, screening and hiring test may be part of the procedure. If you join us, we ask you for a VOG (Certificate of Good Conduct).

Internal candidates will be given priority over external candidates in case of equal suitability.