Assistant professor or postdoc intestinal function and failure

Working at Amsterdam UMC

Assistant professor or postdoc intestinal function and failure

Would you like to take on the challenge of addressing pediatric intestinal failure in a multidisciplinary team?

The project

Intestinal failure is most commonly defined as “the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or fluids and electrolytes, such that intravenous supplementation is required to maintain health and/or growth”. Despite its profound impact, the underlying causes of chronic intestinal failure in children remain poorly understood, and effective therapeutic options are limited.

About your role

• As an Assistant Professor, you will lead cutting-edge translational research with our Tytgat Institute-based research team into the causes of chronic intestinal failure in children, working closely with the clinical team at the pediatric department. You will conduct laboratory-based research at the Tytgat Institute, utilizing its state-of-the-art facilities, while fostering collaboration with clinical colleagues at the Emma Center for Personalized Medicine and the pediatric gastroenterology team at Kinderbuikcentrum Amsterdam UMC. This interdisciplinary approach will allow you to bridge the gap between scientific research and clinical care, identifying novel connections across various research projects.
• In addition to your research responsibilities, you will contribute to teaching by mentoring students and PhD candidates, and translating newly acquired scientific insights into educational resources and knowledge-sharing initiatives. You will also participate in the (Bio)medical curriculum, with teaching expected to constitute 10-20% of your time.
• We expect you to actively contribute to securing research funding and expanding ...

About you

• You hold a PhD in Medicine, Medical Biology, Biochemistry, or a related field.
• You have proven experience in leading, and working with, various research teams.
• You have a strong background in molecular and cellular pathways involved in intestinal development and/or function, with a particular focus on groundbreaking molecular cell biology and genetics.
• Your research aims to uncover innovative therapies for children with chronic intestinal failure.
• As a creative and forward-thinking scientist, you generate hypotheses based on literature insights and input from collaborating clinicians, and design experiments to rigorously test these ideas.
• You demonstrate a track record of successful international collaboration and have the ability to secure competitive funding to expand your research program.
• You are adept at managing the progress and outputs of your team, as well as the financial aspects of multiple, parallel research projects.
• Fluency in both Dutch and English is essential, or a willingness to learn Dutch in the near future to integrate into our ...

Our offer

• The position is initially a temporary appointment for 24 months, with the possibility of extension based on performance.
• The salary depends on your education and experience. Employment conditions are in accordance with the Collective Agreement for University Medical Centers (CAO-UMC).
• Classification in salary scale 10 (postdoc): €3.493 to €5.504, or salary scale 11 (assistant professor): €4.678 to €6.402 gross per month. The salary is exclusive of any irregular hours allowances, holiday pay, and end-of-year bonus. In addition to a good basic salary, we offer 8.3% end-of-year bonus.
• Vacation hours: 190.4 per year for full-time and possibility to save additional hours.
• Free and unlimited access to our online learning environment GoodHabitz.
• Pension accrual with the ABP, of which we pay 70% of the premium.
• A reimbursement of your public transport expenses. Do you prefer to come by bike? Then we have a good bicycle scheme.
• An active staff association and Jong Amsterdam UMC association, both of which organize fun (sports) activities and events.

About your workplace

The primary appointment will be at the AMC location; part-time secondment to the VUmc location is possible.

The Pediatric Abdominal Center at Emma Children’s Hospital/Amsterdam UMC is the leading expert center in the Netherlands for managing this condition, while the Tytgat Institute is a pioneer to pre-clinical research in liver and intestinal diseases. Together, our goal is to advance knowledge of the causes of intestinal failure and develop innovative therapies to improve outcomes for affected children.

Amsterdam UMC has an open culture. This means that we hope that everyone feels welcome in our organization and that we strive to offer equal opportunities to everyone. We therefore cordially invite all interested parties to respond to this vacancy.