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PhD candidates on the projects UltraHB, Bubble-X and Toucan

Posted 24 Mar 2024
Work experience
0 to 3 years
Full-time / part-time
Full-time
Job function
Degree level
Required language
English (Fluent)
Deadline
5 Jan 2020 22:59

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Job description

UltraHB aims at deploying high-framerate ultrasound imaging (1.000 to 10.000 frames per second) techniques to visualize and quantify blood flow from the very slow flows present in the microvessels of the brain to the fast and highly dynamic blood flow in the heart and large blood vessels. This project within the Medical Delta 2.0 program will build on current projects in our group in the fields of cardiovascular flow, brain perfusion, 3D ultrasound imaging and ultrasound contrast agents and will be performed in close collaboration with TU Delft. The PhD student will concentrate on the development of ultrafast ultrasound methods for 2D and 3D flow imaging in the heart and large vessels, with and without contrast agents, up to clinical pilot studies. There will be a close collaboration with researchers and clinicians in related projects. This work will be carried out under the supervision of Dr. J. Voorneveld, Dr. H. Bosch and Prof. N. de Jong.

In Bubble-X we will investigate the potential of high-framerate ultrasound imaging of novel monodisperse microbubbles and explore their unique properties: 1) for 3D flow quantification and 2) for obtaining the ‘holy grail’ of non-invasive intraluminal pressure estimation, in the large blood vessels. This project is part of the NWO-TTW Perspectief program Ultra-X-treme on 3D high-framerate vascular ultrasound imaging, a collaboration between five Dutch universities and eight industrial partners. The PhD student will focus on high-framerate imaging approaches aimed at exploitation of the properties of monodisperse microbubbles for 2D/3D flow assessment and pressure estimation. There will be a close collaboration with the Physics of Fluids group, TU Twente. Also, there will be many opportunities for collaborative research with clinicians and technical researchers. The PhD student will work under the supervision of Dr. J. Voorneveld and Prof. N. de Jong.

Toucan: we have recently shown that ideas from compressive sensing provide a novel and attractive approach to bring 3D imaging to many applications: a simple plastic coding mask can compress the 3D information in such a way that you need far less sensors. This concept can extend the imaging capabilities of commercial 2D ultrasound probes to 3D, but also enables new types of wearable imaging. The PhD will work on compressive imaging devices that can be used to image the human carotid artery for diagnostic purposes. The research will specifically focus on: 1) 3D ultrasound imaging of atherosclerotic plaques using a regular probe and coding mask, 2) long-term monitoring of the pulse-wave velocity and other cardiovascular parameters inside the carotid artery. This work will be carried out under the supervision of Dr. H.Bosch, in collaboration with Neuroscience and the Circuits & Systems group at TU Delft and researchers working on the compressive sensing signal processing and the application in mouse brain imaging.

Work environment

Erasmus MC stands for a healthy population and excellence in healthcare. By conducting groundbreaking work, we aim to push boundaries through leading the way in research, education and healthcare. We have access to the latest equipment and techniques in a state-of-the-art environment.

The Department of Biomedical Engineering (Thorax Center) is a group of over 50 researchers performing highly innovative research in cardiovascular diagnosis and therapy. We focus on translational research in ultrasound imaging and image processing, ultrasound contrast agents for molecular imaging and drug delivery, intravascular imaging techniques and hemodynamics. The Biomedical Engineering Department is composed of engineers, biologists and clinicians, closely collaborating on cutting-edge cardiovascular research. Its vibrant working environment attracts highly motivated researchers from all over the world.

Qualifications and skills

We are seeking enthusiastic PhD students that meet the following requirements:

  • A MSc in a relevant area (Electrical Engineering, Applied Physics, Biomedical Engineering), with knowledge of or affinity with ultrasound imaging, ultrasound image processing and/or signal processing;
  • Experience with programming (Matlab, Python, C++);
  • Experience in measurements/experimental setups;
  • Creative, pro-active with good analytical skills and a sound academic attitude;
  • Excellent communication skills in English, both in writing and speaking;
  • Good team-players and able to work in a collaborative environment with other PhD students/researchers and supporting institutions.

Being able to present a certificate of good conduct, a valid proof of identity, diplomas and/ or relevant registration such as BIG/ RGS are conditions for the appointment.

Terms of employment

You will receive a temporary position of 4 years. The gross monthly salary is € 2.422,- in the 1st year and increases to € 3.103,- in the 4th year (scale OIO). The terms of employment are according to the Collective Bargaining Agreement for Dutch University Medical Centers (CAO UMC).

Information and application

For more information about PhD positions please contact Dr.ir. Hans Bosch, Associate Professor, phone number: +31(0)10 703 80 88 or e-mail: j.bosch@erasmusmc.nl . For other information please contact Mrs Sharon Sewell, secretary, phone number: +31(0)10 704 40 30 or e-mail: s.sewell-albert@erasmusmc.nl.

If you are excited by the thought of this position and would like to apply, please do so by using the application form on our website and include: 1) a CV including names and contact information of two references who are acquainted with your previous academic and/or research/professional activity; 2) transcripts from BSc and MSc degrees and 3) a motivation on why you want to join the group (max. 1 page).

We are Erasmus MC. Our roots lie in Rotterdam, a city and port of international standing. We are the most innovative university medical center in the Netherlands and one of the world’s leading centers of scientific research.

Healthcare
Rotterdam
10,000 employees